Athens, Ga. – Researchers at the University of Georgia’s Regenerative Bioscience Center have developed Brain Glue, a substance that could one day serve as a treatment for traumatic brain injuries, or TBIs. The Brain Glue is a hydrogel matrix with a gelatin-like consistency that acts as a scaffolding for transplanted stem cells, which are capable of repairing damaged tissue. With the unique ability to take the shape of the void left in the brain after a severe trauma, the Brain Glue will enable a more natural healing environment for stem cells to colonize and regenerate.Lohitash Karumbaiah, assistant professor in UGA’s College of Agricultural and Environmental Sciences, led the team that designed and created Brain Glue. The main difference between Brain Glue and other synthetic hydrogels, according to the team, is the variety of possibilities to trap neural stem cells, improve integration and reduce the likelihood of rejection. “It’s very common with these invasive injuries that surgeons will actually remove the part of the dead brain leaving behind a cavity or hole,” said Karumbaiah. “The question is, then, can you replace that with something like our Brain Glue, loaded up with compounds native to the brain together with a mix of protective agents that can be incorporated for the best therapeutic outcome. “The cool thing about this chemistry is that you can take our Brain Glue liquid formulation and then very briefly expose it to long-wave UV light and form a hydrogel in any shape you like,” he said. Every day, 153 people in the U.S. die from injuries that include TBI, according to the Centers for Disease Control and Prevention. Those who survive a TBI may live with impaired thinking, memory, movement or sensation. TBIs can also lead to personality and emotional changes. The new approach is described in the journal ACS Biomaterials Science and Engineering and a recently awarded abstract from the International Brain Injury Association. For more than two years now, Karumbaiah has been awarded seed-funding for his collaborative TBI work with Maysam Ghovanloo, associate professor of electrical and computer engineering at the Georgia Institute of Technology. The TBI research was initially funded by the Center for Regenerative Engineering & Medicine, known as REM, a collaborative initiative launched in 2011 between the University of Georgia, Emory University and the Georgia Institute of Technology. The REM collaboration is an extension of Karumbaiah’s work to further study neuroplasticity: the brain’s ability to self-renew, adapt and compensate for injury and disease. His future studies will focus on how neural networks form and change in response to traumatic insults, and he will investigate the therapeutic use of electrical stimulation to help return loss of function in any given region of the brain. “Multiple methods are needed in these kinds of studies,” said Karumbaiah. “The Brain Glue is where we make the scaffold, and the neuro-network function is really this other arm—learning how neurons fire and wire together and what this really means in terms of function.” Steven Stice, director of the Regenerative Bioscience Center, is working with Karumbaiah on a licensed technology for commercialization of the new Brain Glue, which was recently named best abstract at a meeting of the International Brain Injury Association.Karumbaiah’s work recently attracted a four-year, $1.5 million research grant from the National Institutes of Health. “Lohitash sets an example for other junior faculty to emulate,” said Stice, GRA Eminent Scholar and D.W. Brooks Professor in CAES. “To be recognized internationally at such an early stage takes great skill and dedication.” A full version of ACS Biomaterials Science article is available online at pubs.acs.org/doi/pdf/10.1021/acsbiomaterials.6b00805. The Regenerative Bioscience Center at the University of Georgia links researchers and resources collaborating in a wide range of disciplines to develop new cures for devastating diseases that affect animals and people. With its potential restorative powers, regenerative medicine could offer new ways of treating diseases for which there are currently no treatments—including heart disease, Parkinson’s, Alzheimer’s and stroke. For more information, see www.rbc.uga.edu.
Tampa police arrested a man who reportedly threatened to blow up the Hillsborough County Sheriff’s Office.Joshua Cramer, 32, is charged with Threatening to Discharge Destructive Device.On June 23 around 9 a.m., the suspect called Tampa Police and said he was upset with HCSO and, that he was out of town but planned on blowing up an HSCO annex office located in Ybor City when he returned.Cramer was arrested at his home by The Tampa Police Department on Tuesday.Police say an investigation into the matter is ongoing but did not release further details.This story is developing.
Image Courtesy: FPJ/GettyAdvertisement yqydNBA Finals | Brooklyn VsaWingsuit rodeo📽Sindre Eusba( IG: @_aubreyfisher @imraino ) 4hWould you ever consider trying this?😱btnyqCan your students do this? 🌚1k3sihpRoller skating! Powered by Firework Jwala Gutta, India’s badminton icon and one of the most inspiring sportspersons of the country, has often made headlines for her outspoken nature. However, Jwala recently revealed that being straightforward had her facing difficulty in career, and the sole person she holds accountable for the damage is none other than the national chief badminton coach and Jwala’s former doubles partner Pullela Gopichand!Advertisement Image Courtesy: FPJ/GettyJwala and Gopichand formed the team that National Badminton Championship title in mixed doubles back in 2004. However, as time passed, and the two shuttling icons of the country became distant.The former world no. 6 recently opened up about her relation with Gopichand, and accused Gopichand for partiality in badminton coaching system and also numerous career scopes Jwala missed in her career.Advertisement Speaking to India Today, Jwala revealed aggravation she faced in the past because of Gopichand, and how her straight from the shoulder attitude had bitten her back.“I hold him (Gopichand) responsible for the harassment I had to go through all these years. I am vocal and I have had to pay a huge price for that,” the 36 year old shuttler said in the interview.Advertisement “I acknowledge what he (Gopi) has achieved and I had expectations from him. Gopi knows my potential and what I was capable of,” the 2010 Commonwealth Games gold medallist continued, “He was part of the establishment and he knew my potential, so it was quite natural for me to have expectations from him.”Jwala further blamed Gopichand for favouritism and making the sport of badminton in the country centralised: “If you notice, there were players from other states when Gopi used to play. So there was a time where top players used to come from different parts of the country.”Jwala further stated that Gopichand, being from Andhra Pradesh, favours shuttlers from his state, and is the reason why the Indian badminton scene has a domination of Telugu players or players from Hyderabad.“If India wins a medal, it is because of Gopichand and if we don’t do well, then it is the system that is to be blamed,” she further added.In addition to that, Jwala also revealed facing racism and xenophobia, for having a Chinese mother. She recently took to social media to reveal how she was targeted as the ‘Boycott Chinese Product’ movement gained pace among the netizens of the country.“People have a lot of time to waste on such things, calling someone ‘Chinese’. It was important to call out people like these. So it is my duty to teach these people a lesson and tell them that the power of anonymity has its consequences too,” Jwala said.If you like reading about MMA, make sure you check out MMAIndia.com Also follow India’s biggest arm wrestling tournament at ProPanja.comAlso read-Former Ranji trophy cricketer found dead; son arrested for murder Advertisement